Peripheral Nerve Injury Guide

Clinical Features, Deformities & Classification

Upper Limb

Lower Limb

Nerve Injury Classification

Comparison of Seddon's (1943) and Sunderland's (1951) systems.

Seddon	Sunderland	Pathology	Prognosis
Neurapraxia	Grade I	Physiological block (Myelin damage). Axon intact. No Wallerian Degeneration.	Excellent (Days to Weeks). Complete recovery.
Axonotmesis	Grade II	Axon severed. Endoneurium intact.	Good (1mm/day). Guided by endoneurial tube.
	Grade III	Axon + Endoneurium disrupted. Perineurium intact.	Fair. Scarring may block regeneration.
	Grade IV	Axon + Endo + Perineurium disrupted. Epineurium intact.	Poor. Neuroma formation likely. Surgery needed.
Neurotmesis	Grade V	Complete transection of nerve trunk.	None without Surgery. Repair/Graft required.